# Vitamin D Blood Pressure Randomized Trial: What the Evidence Says
Canonical: https://www.migaku.app/guides/vitamin-d-blood-pressure-randomized-trial-evidence-review
Category: evidence-review
Summary: Vitamin D Blood Pressure Randomized Trial has 2 source documents in the current Migaku evidence database. The strongest available sources in this first pass a
Last reviewed: 2026-08-18
Reviewed by: Migaku Evidence Review
# Vitamin D Blood Pressure Randomized Trial: What the Evidence Says

## Quick Answer

Vitamin D Blood Pressure Randomized Trial has 2 source documents in the current Migaku evidence database. The strongest available sources in this first pass are randomized trial, so conclusions should be framed as evidence-aware guidance rather than medical advice.

## Key Takeaways

- This page is generated only from sources stored in the Migaku evidence knowledge base.
- Current evidence mix: 2 randomized trial.
- Claims should be interpreted with the source type, study design, population, and publication date in mind.
- This article is educational and does not replace care from a qualified clinician.

## Evidence Map

| Source | Evidence type | Level | Date | Identifier |
| --- | --- | ---: | --- | --- |
| Vitamin C Supplementation in Hospitalized Patients With Community-Acquired Pneumonia: Protocol for a Randomized Controlled Trial | randomized trial | 2 | 2026-01-01 | 10.2196/91037 |
| Effects of peppermint ( Mentha x piperita L.) oil on cardiometabolic outcomes in patients with pre- and stage 1 hypertension: A placebo randomized controlled trial | randomized trial | 2 | 2026-04-23 | 10.1371/journal.pone.0344538 |

## What The Sources Report

- P P Hypovitaminosis C is common in acute illness due to increased metabolic demand, reduced intake, and enhanced losses and has been associated with worse outcomes in sepsis and pneumonia. [Schwartz Amy (2026); evidence level 2]
- There was a trend toward increased in-hospital mortality (adjusted odds ratio 4.23, 95% CI 0.58-30.48) and 30-day mortality (adjusted odds ratio 3.82, 95% CI 0.71-20.50) among patients who had vitamin C deficiency. [Schwartz Amy (2026); evidence level 2]
- Globally, hypertension is renowned as the leading risk factor for cardiovascular disease morbidity and mortality. [Sinclair Jonathan (2026); evidence level 2]
- High blood pressure ranks first among modifiable risk factors attributable to cardiovascular disease aetiology, accounting for the largest proportion of coronary heart disease, heart failure, and stroke events. [Sinclair Jonathan (2026); evidence level 2]

## How To Read This Evidence

Evidence level 1 generally reflects systematic reviews or meta-analyses. Level 2 includes randomized trials, guidelines, or public-health guidance. Level 3 usually reflects observational or narrative-review evidence. Level 4 is weaker or early-stage evidence. The level is a sorting aid, not a final quality grade.

## Practical Interpretation

There is trial evidence in the current set, but population and intervention details still matter. For vitamin D blood pressure randomized trial, the next editorial step is to add more targeted sources and separate strong findings from early or indirect evidence.

## Limits Of This First Pass

This is a small-batch MVP article. It uses the first ingested sources for this topic and should be expanded with more targeted searches, license review, and human editorial checks before being treated as a definitive review.

## References

- Schwartz Amy (2026). Vitamin C Supplementation in Hospitalized Patients With Community-Acquired Pneumonia: Protocol for a Randomized Controlled Trial. DOI: 10.2196/91037. PMCID: PMC13173059. PMID: 42054676. License: CC BY 4.0. https://pmc.ncbi.nlm.nih.gov/articles/PMC13173059/
- Sinclair Jonathan (2026). Effects of peppermint ( Mentha x piperita L.) oil on cardiometabolic outcomes in patients with pre- and stage 1 hypertension: A placebo randomized controlled trial. DOI: 10.1371/journal.pone.0344538. PMCID: PMC13105356. PMID: 42024666. License: CC BY 4.0. https://pmc.ncbi.nlm.nih.gov/articles/PMC13105356/

## Safety Note

Health information can change, and individual risk depends on medical history, medications, pregnancy status, age, and diagnosis. Talk with a qualified clinician before changing treatment, supplement, or medication routines.