# Spirulina Fatigue Meta-analysis: What the Evidence Says
Canonical: https://www.migaku.app/guides/spirulina-fatigue-meta-analysis-evidence-review
Category: evidence-review
Summary: Spirulina Fatigue Meta-analysis has 2 source documents in the current Migaku evidence database. The strongest available sources in this first pass are systema
Last reviewed: 2026-06-09
Reviewed by: Migaku Evidence Review
# Spirulina Fatigue Meta-analysis: What the Evidence Says

## Quick Answer

Spirulina Fatigue Meta-analysis has 2 source documents in the current Migaku evidence database. The strongest available sources in this first pass are systematic review, so conclusions should be framed as evidence-aware guidance rather than medical advice.

## Key Takeaways

- This page is generated only from sources stored in the Migaku evidence knowledge base.
- Current evidence mix: 1 systematic review, 1 preclinical study.
- Claims should be interpreted with the source type, study design, population, and publication date in mind.
- This article is educational and does not replace care from a qualified clinician.

## Evidence Map

| Source | Evidence type | Level | Date | Identifier |
| --- | --- | ---: | --- | --- |
| The Effects of Seaweed and Microalgae Supplementation on Exercise Performance and Recovery: A Systematic Review and Meta-Analysis | systematic review | 1 | 2026-04-19 | 10.3390/nu18081289 |
| PHARMACOLOGICAL TREATMENTS FOR FATIGUE IN INFLAMMATORY BOWEL DISEASE PATIENTS: AN INTEGRATIVE REVIEW | preclinical study | 4 | 2026-01-09 | 10.1590/S0004-2803.24612025-081 |

## What The Sources Report

- Astaxanthin derived fromhas attracted considerable attention due to its potent antioxidant capacity; however, evidence regarding its effects on exercise performance and recovery remains inconsistent. [Wei Yan (2026); evidence level 1]
- By integrating available evidence, this study sought to evaluate the dual effects of algae supplementation on exercise performance and recovery, identify intervention characteristics associated with greater efficacy, and provide more targeted evidence for sports nutrition practice, and guide the design of future high-quality RCTs. [Wei Yan (2026); evidence level 1]
- The etiology of fatigue in IBD is multifactorial and may be associated with inflammation, anemia, nutrient deficiencies, medications, and microbiota. [MORAIS Tayane (2026); evidence level 4]
- Fatigue in patients with IBD is associated with decreased physical functioning, mood disturbances, and low productivity, presenting symptoms of physical and mental exhaustion. [MORAIS Tayane (2026); evidence level 4]

## How To Read This Evidence

Evidence level 1 generally reflects systematic reviews or meta-analyses. Level 2 includes randomized trials, guidelines, or public-health guidance. Level 3 usually reflects observational or narrative-review evidence. Level 4 is weaker or early-stage evidence. The level is a sorting aid, not a final quality grade.

## Practical Interpretation

There is at least one systematic-review style source in the current set, so it deserves more weight than single-study evidence. For spirulina fatigue meta-analysis, the next editorial step is to add more targeted sources and separate strong findings from early or indirect evidence.

## Limits Of This First Pass

This is a small-batch MVP article. It uses the first ingested sources for this topic and should be expanded with more targeted searches, license review, and human editorial checks before being treated as a definitive review.

## References

- Wei Yan (2026). The Effects of Seaweed and Microalgae Supplementation on Exercise Performance and Recovery: A Systematic Review and Meta-Analysis. DOI: 10.3390/nu18081289. PMCID: PMC13119196. PMID: 42075102. License: CC BY 4.0. https://pmc.ncbi.nlm.nih.gov/articles/PMC13119196/
- MORAIS Tayane (2026). PHARMACOLOGICAL TREATMENTS FOR FATIGUE IN INFLAMMATORY BOWEL DISEASE PATIENTS: AN INTEGRATIVE REVIEW. DOI: 10.1590/S0004-2803.24612025-081. PMCID: PMC12788763. PMID: 41538673. License: CC BY 4.0. https://pmc.ncbi.nlm.nih.gov/articles/PMC12788763/

## Safety Note

Health information can change, and individual risk depends on medical history, medications, pregnancy status, age, and diagnosis. Talk with a qualified clinician before changing treatment, supplement, or medication routines.