# Pumpkin Seed Oil Skin Randomized Trial: What the Evidence Says
Canonical: https://www.migaku.app/guides/pumpkin-seed-oil-skin-randomized-trial-evidence-review
Category: evidence-review
Summary: Pumpkin Seed Oil Skin Randomized Trial has 2 source documents in the current Migaku evidence database. The strongest available sources in this first pass are 
Last reviewed: 2026-07-28
Reviewed by: Migaku Evidence Review
# Pumpkin Seed Oil Skin Randomized Trial: What the Evidence Says

## Quick Answer

Pumpkin Seed Oil Skin Randomized Trial has 2 source documents in the current Migaku evidence database. The strongest available sources in this first pass are systematic review, randomized trial, so conclusions should be framed as evidence-aware guidance rather than medical advice.

## Key Takeaways

- This page is generated only from sources stored in the Migaku evidence knowledge base.
- Current evidence mix: 1 systematic review, 1 randomized trial.
- Claims should be interpreted with the source type, study design, population, and publication date in mind.
- This article is educational and does not replace care from a qualified clinician.

## Evidence Map

| Source | Evidence type | Level | Date | Identifier |
| --- | --- | ---: | --- | --- |
| Effects of dietary supplements on androgenetic alopecia: a systematic review and network meta-analysis | systematic review | 1 | 2026-01-05 | 10.3389/fnut.2025.1719711 |
| Efficacy of Flaxseed Oil in Treating Mild to Moderate Psoriasis Vulgaris Compared with Topical Betamethasone: A Randomized, Double-Blind, Clinical Trial | randomized trial | 2 | 2025-01-01 | 10.4103/abr.abr_559_24 |

## What The Sources Report

- The diameter of the hair shaft becomes thinner, pigmentation decreases, and the result is visibly progressive hair loss. [Zhou Lei (2026); evidence level 1]
- This definition and screening process aimed to reduce bias and ensure consistency in the evidence strength and comparability of the included interventions. [Zhou Lei (2026); evidence level 1]
- Statistical analysis revealed that after 4 weeks, flaxseed oil, compared to betamethasone, significantly reduced the PASI score and improved the quality of life (= 0.001). [Mohammadian Rasanan Farshad (2025); evidence level 2]
- Psoriasis is a common disorder involving inflammation and immune responses and is characterized by increased levels of inflammatory mediators and epidermal hyperplasia in skin lesions. [Mohammadian Rasanan Farshad (2025); evidence level 2]

## How To Read This Evidence

Evidence level 1 generally reflects systematic reviews or meta-analyses. Level 2 includes randomized trials, guidelines, or public-health guidance. Level 3 usually reflects observational or narrative-review evidence. Level 4 is weaker or early-stage evidence. The level is a sorting aid, not a final quality grade.

## Practical Interpretation

There is at least one systematic-review style source in the current set, so it deserves more weight than single-study evidence. There is trial evidence in the current set, but population and intervention details still matter. For pumpkin seed oil skin randomized trial, the next editorial step is to add more targeted sources and separate strong findings from early or indirect evidence.

## Limits Of This First Pass

This is a small-batch MVP article. It uses the first ingested sources for this topic and should be expanded with more targeted searches, license review, and human editorial checks before being treated as a definitive review.

## References

- Zhou Lei (2026). Effects of dietary supplements on androgenetic alopecia: a systematic review and network meta-analysis. DOI: 10.3389/fnut.2025.1719711. PMCID: PMC12812558. PMID: 41561175. License: CC BY 4.0. https://pmc.ncbi.nlm.nih.gov/articles/PMC12812558/
- Mohammadian Rasanan Farshad (2025). Efficacy of Flaxseed Oil in Treating Mild to Moderate Psoriasis Vulgaris Compared with Topical Betamethasone: A Randomized, Double-Blind, Clinical Trial. DOI: 10.4103/abr.abr_559_24. PMCID: PMC12885202. PMID: 41669307. License: https://creativecommons.org/licenses/by-nc-nd/4.0/. https://pmc.ncbi.nlm.nih.gov/articles/PMC12885202/

## Safety Note

Health information can change, and individual risk depends on medical history, medications, pregnancy status, age, and diagnosis. Talk with a qualified clinician before changing treatment, supplement, or medication routines.