# Magnesium Glycinate Anxiety Randomized Trial: What the Evidence Says
Canonical: https://www.migaku.app/guides/magnesium-glycinate-anxiety-randomized-trial-evidence-review
Category: evidence-review
Summary: Magnesium Glycinate Anxiety Randomized Trial has 2 source documents in the current Migaku evidence database. The strongest available sources in this first pas
Last reviewed: 2026-06-04
Reviewed by: Migaku Evidence Review
# Magnesium Glycinate Anxiety Randomized Trial: What the Evidence Says

## Quick Answer

Magnesium Glycinate Anxiety Randomized Trial has 2 source documents in the current Migaku evidence database. The strongest available sources in this first pass are systematic review, so conclusions should be framed as evidence-aware guidance rather than medical advice.

## Key Takeaways

- This page is generated only from sources stored in the Migaku evidence knowledge base.
- Current evidence mix: 1 systematic review, 1 narrative review.
- Claims should be interpreted with the source type, study design, population, and publication date in mind.
- This article is educational and does not replace care from a qualified clinician.

## Evidence Map

| Source | Evidence type | Level | Date | Identifier |
| --- | --- | ---: | --- | --- |
| Unlocking the Power of Magnesium: A Systematic Review and Meta-Analysis Regarding Its Role in Oxidative Stress and Inflammation. | systematic review | 1 | 2025-06-16 | 10.3390/antiox14060740 |
| Magnesium: Health Effects, Deficiency Burden, and Future Public Health Directions | narrative review | 3 | 2025-11-20 | 10.3390/nu17223626 |

## What The Sources Report

- Magnesium plays a crucial role in over 300 enzymatic reactions related to energy production, muscle contraction, and nerve function. [Cepeda V (2025); evidence level 1]
- Given its essential biological functions and increasing prevalence of suboptimal intake, magnesium supplementation has gained attention for its potential health benefits, particularly in mitigating oxidative stress and inflammation. [Cepeda V (2025); evidence level 1]
- Adequate magnesium status supports muscle contraction and relaxation, regulates electrolyte balance, and enhances exercise capacity as well as post-exercise recovery, whereas deficiency is associated with fatigue, weakness, and impaired physical performance. [Matek Sarić Marijana (2025); evidence level 3]
- Growing evidence links insufficient intake to hypertension, type 2 diabetes, osteoporosis, migraines, depression, and chronic inflammation. [Matek Sarić Marijana (2025); evidence level 3]

## How To Read This Evidence

Evidence level 1 generally reflects systematic reviews or meta-analyses. Level 2 includes randomized trials, guidelines, or public-health guidance. Level 3 usually reflects observational or narrative-review evidence. Level 4 is weaker or early-stage evidence. The level is a sorting aid, not a final quality grade.

## Practical Interpretation

There is at least one systematic-review style source in the current set, so it deserves more weight than single-study evidence. For magnesium glycinate anxiety randomized trial, the next editorial step is to add more targeted sources and separate strong findings from early or indirect evidence.

## Limits Of This First Pass

This is a small-batch MVP article. It uses the first ingested sources for this topic and should be expanded with more targeted searches, license review, and human editorial checks before being treated as a definitive review.

## References

- Cepeda V (2025). Unlocking the Power of Magnesium: A Systematic Review and Meta-Analysis Regarding Its Role in Oxidative Stress and Inflammation.. DOI: 10.3390/antiox14060740. PMCID: PMC12189353. PMID: 40563371. https://pmc.ncbi.nlm.nih.gov/articles/PMC12189353/
- Matek Sarić Marijana (2025). Magnesium: Health Effects, Deficiency Burden, and Future Public Health Directions. DOI: 10.3390/nu17223626. PMCID: PMC12655508. PMID: 41305676. License: CC BY 4.0. https://pmc.ncbi.nlm.nih.gov/articles/PMC12655508/

## Safety Note

Health information can change, and individual risk depends on medical history, medications, pregnancy status, age, and diagnosis. Talk with a qualified clinician before changing treatment, supplement, or medication routines.