# Ketone Supplement Exercise Performance Meta-analysis: What the Evidence Says Canonical: https://www.migaku.app/guides/ketone-supplement-exercise-performance-meta-analysis-evidence-review Category: evidence-review Summary: Ketone Supplement Exercise Performance Meta-analysis has 2 source documents in the current Migaku evidence database. The strongest available sources in this f Last reviewed: 2026-08-12 Reviewed by: Migaku Evidence Review # Ketone Supplement Exercise Performance Meta-analysis: What the Evidence Says ## Quick Answer Ketone Supplement Exercise Performance Meta-analysis has 2 source documents in the current Migaku evidence database. The strongest available sources in this first pass are systematic review, so conclusions should be framed as evidence-aware guidance rather than medical advice. ## Key Takeaways - This page is generated only from sources stored in the Migaku evidence knowledge base. - Current evidence mix: 1 systematic review, 1 research article. - Claims should be interpreted with the source type, study design, population, and publication date in mind. - This article is educational and does not replace care from a qualified clinician. ## Evidence Map | Source | Evidence type | Level | Date | Identifier | | --- | --- | ---: | --- | --- | | The effect of exogenous ketone bodies on cognition across health and disease: a systematic review and meta-analysis | systematic review | 1 | 2026-04-15 | 10.3389/fnut.2026.1802531 | | An extract from whole Coffea arabica coffee cherry improves time trial performance, but not muscle glycogen resynthesis, in trained cyclists | research article | 4 | 2026-06-03 | 10.1080/15502783.2026.2682323 | ## What The Sources Report - In addition to the reduced quality of life and wellbeing for the patient, ADRD also imposes a cost on society through the significant financial burden of patient care. [Bonnechère Bruno (2026); evidence level 1] - All participants met the classification of being Tier 2 athletes, and habitual caffeine use was chosen to minimize the risk of adverse events from unaccustomed caffeine intake. [Pavis George F. (2026); evidence level 4] - From baseline, plasma caffeine concentration remained unchanged with PLA throughout SS, but was elevated by CB immediately prior to, and at 10, 20 and 30 mins of SS (interaction < 0.001; all timepoints increased from baseline, and greater than PLA; post hoc < 0.001). [Pavis George F. (2026); evidence level 4] ## How To Read This Evidence Evidence level 1 generally reflects systematic reviews or meta-analyses. Level 2 includes randomized trials, guidelines, or public-health guidance. Level 3 usually reflects observational or narrative-review evidence. Level 4 is weaker or early-stage evidence. The level is a sorting aid, not a final quality grade. ## Practical Interpretation There is at least one systematic-review style source in the current set, so it deserves more weight than single-study evidence. For ketone supplement exercise performance meta-analysis, the next editorial step is to add more targeted sources and separate strong findings from early or indirect evidence. ## Limits Of This First Pass This is a small-batch MVP article. It uses the first ingested sources for this topic and should be expanded with more targeted searches, license review, and human editorial checks before being treated as a definitive review. ## References - Bonnechère Bruno (2026). The effect of exogenous ketone bodies on cognition across health and disease: a systematic review and meta-analysis. DOI: 10.3389/fnut.2026.1802531. PMCID: PMC13127162. PMID: 42063954. License: CC BY 4.0. https://pmc.ncbi.nlm.nih.gov/articles/PMC13127162/ - Pavis George F. (2026). An extract from whole Coffea arabica coffee cherry improves time trial performance, but not muscle glycogen resynthesis, in trained cyclists. DOI: 10.1080/15502783.2026.2682323. PMCID: PMC13235231. PMID: 42234539. License: CC BY 4.0. https://pmc.ncbi.nlm.nih.gov/articles/PMC13235231/ ## Safety Note Health information can change, and individual risk depends on medical history, medications, pregnancy status, age, and diagnosis. Talk with a qualified clinician before changing treatment, supplement, or medication routines.