# Iron Exercise Performance Meta-analysis: What the Evidence Says
Canonical: https://www.migaku.app/guides/iron-exercise-performance-meta-analysis-evidence-review
Category: evidence-review
Summary: Iron Exercise Performance Meta-analysis has 2 source documents in the current Migaku evidence database. The strongest available sources in this first pass are
Last reviewed: 2026-07-08
Reviewed by: Migaku Evidence Review
# Iron Exercise Performance Meta-analysis: What the Evidence Says

## Quick Answer

Iron Exercise Performance Meta-analysis has 2 source documents in the current Migaku evidence database. The strongest available sources in this first pass are systematic review, so conclusions should be framed as evidence-aware guidance rather than medical advice.

## Key Takeaways

- This page is generated only from sources stored in the Migaku evidence knowledge base.
- Current evidence mix: 1 systematic review, 1 research article.
- Claims should be interpreted with the source type, study design, population, and publication date in mind.
- This article is educational and does not replace care from a qualified clinician.

## Evidence Map

| Source | Evidence type | Level | Date | Identifier |
| --- | --- | ---: | --- | --- |
| The Effects of Seaweed and Microalgae Supplementation on Exercise Performance and Recovery: A Systematic Review and Meta-Analysis | systematic review | 1 | 2026-04-19 | 10.3390/nu18081289 |
| Effects of exercise in cool versus hot conditions on pathways of gut permeability, systemic inflammation, and iron homeostasis in female athletes | research article | 4 | 2026-06-17 | 10.14814/phy2.70981 |

## What The Sources Report

- Astaxanthin derived fromhas attracted considerable attention due to its potent antioxidant capacity; however, evidence regarding its effects on exercise performance and recovery remains inconsistent. [Wei Yan (2026); evidence level 1]
- By integrating available evidence, this study sought to evaluate the dual effects of algae supplementation on exercise performance and recovery, identify intervention characteristics associated with greater efficacy, and provide more targeted evidence for sports nutrition practice, and guide the design of future high-quality RCTs. [Wei Yan (2026); evidence level 1]
- Hepcidin functions by blocking the only known cellular iron-exporting channel (ferroportin) leading to reduced iron availability in circulation and reduced absorption of dietary iron (Ganz & Nemeth, ). [Lucernoni Kathryn M. (2026); evidence level 4]
- Exercise in hot environmental conditions can result in higher IL-6 production due to changes in relative exercise intensity (McKay et al., ) and previous work in a field-based investigation showed a positive correlation between ambient temperature and hepcidin concentration (McKay et al., ). [Lucernoni Kathryn M. (2026); evidence level 4]

## How To Read This Evidence

Evidence level 1 generally reflects systematic reviews or meta-analyses. Level 2 includes randomized trials, guidelines, or public-health guidance. Level 3 usually reflects observational or narrative-review evidence. Level 4 is weaker or early-stage evidence. The level is a sorting aid, not a final quality grade.

## Practical Interpretation

There is at least one systematic-review style source in the current set, so it deserves more weight than single-study evidence. For iron exercise performance meta-analysis, the next editorial step is to add more targeted sources and separate strong findings from early or indirect evidence.

## Limits Of This First Pass

This is a small-batch MVP article. It uses the first ingested sources for this topic and should be expanded with more targeted searches, license review, and human editorial checks before being treated as a definitive review.

## References

- Wei Yan (2026). The Effects of Seaweed and Microalgae Supplementation on Exercise Performance and Recovery: A Systematic Review and Meta-Analysis. DOI: 10.3390/nu18081289. PMCID: PMC13119196. PMID: 42075102. License: CC BY 4.0. https://pmc.ncbi.nlm.nih.gov/articles/PMC13119196/
- Lucernoni Kathryn M. (2026). Effects of exercise in cool versus hot conditions on pathways of gut permeability, systemic inflammation, and iron homeostasis in female athletes. DOI: 10.14814/phy2.70981. PMCID: PMC13276288. PMID: 42311035. License: CC BY 4.0. https://pmc.ncbi.nlm.nih.gov/articles/PMC13276288/

## Safety Note

Health information can change, and individual risk depends on medical history, medications, pregnancy status, age, and diagnosis. Talk with a qualified clinician before changing treatment, supplement, or medication routines.