# Hops Sleep Randomized Trial: What the Evidence Says
Canonical: https://www.migaku.app/guides/hops-sleep-randomized-trial-evidence-review
Category: evidence-review
Summary: Hops Sleep Randomized Trial has 2 source documents in the current Migaku evidence database. The strongest available sources in this first pass are randomized 
Last reviewed: 2026-07-07
Reviewed by: Migaku Evidence Review
# Hops Sleep Randomized Trial: What the Evidence Says

## Quick Answer

Hops Sleep Randomized Trial has 2 source documents in the current Migaku evidence database. The strongest available sources in this first pass are randomized trial, so conclusions should be framed as evidence-aware guidance rather than medical advice.

## Key Takeaways

- This page is generated only from sources stored in the Migaku evidence knowledge base.
- Current evidence mix: 2 randomized trial.
- Claims should be interpreted with the source type, study design, population, and publication date in mind.
- This article is educational and does not replace care from a qualified clinician.

## Evidence Map

| Source | Evidence type | Level | Date | Identifier |
| --- | --- | ---: | --- | --- |
| Integrative therapies for chronic insomnia: A randomized controlled trial of a traditional Thai Herbal Remedy and Cannabis sativa oil | randomized trial | 2 | 2026-12-01 | 10.1016/j.sleepx.2026.100173 |
| Effects of a Valerian‐Hops Extract Combination (Ze 91019) on Sleep Duration and Daytime Cognitive and Psychological Parameters in Occasional Insomnia: A Randomized Controlled Feasibility Trial | randomized trial | 2 | 2025-06-04 | 10.1002/brb3.70600 |

## What The Sources Report

- Insomnia is a pervasive sleep disorder characterized by persistent difficulties in initiating or maintaining sleep or experiencing nonrestorative sleep despite adequate opportunity, leading to daytime impairment and reduced quality of life. [Pakdee Naruwat (2026); evidence level 2]
- Pharmacological treatments using benzodiazepines, such as lorazepam, are standard for managing moderate to severe insomnia and anxiety-associated sleep disturbances owing to their efficacy and rapid onset of action. [Pakdee Naruwat (2026); evidence level 2]
- We also found a significant prolongation of the total duration in bed during the night (= 0.023,= 0.37) with an estimated increase in the duration in bed of 0.406 h (24.4 min) in the verum group compared to the placebo group (Table ). [Schicktanz Nathalie (2025); evidence level 2]
- The exploratory analysis indicated that the valerian and hop-fixed herbal combination (Ze 91019) significantly increased sleep duration compared to placebo, with an average increase of 21.7 min per night during the treatment period as measured by the Fitbit tracker. [Schicktanz Nathalie (2025); evidence level 2]

## How To Read This Evidence

Evidence level 1 generally reflects systematic reviews or meta-analyses. Level 2 includes randomized trials, guidelines, or public-health guidance. Level 3 usually reflects observational or narrative-review evidence. Level 4 is weaker or early-stage evidence. The level is a sorting aid, not a final quality grade.

## Practical Interpretation

There is trial evidence in the current set, but population and intervention details still matter. For hops sleep randomized trial, the next editorial step is to add more targeted sources and separate strong findings from early or indirect evidence.

## Limits Of This First Pass

This is a small-batch MVP article. It uses the first ingested sources for this topic and should be expanded with more targeted searches, license review, and human editorial checks before being treated as a definitive review.

## References

- Pakdee Naruwat (2026). Integrative therapies for chronic insomnia: A randomized controlled trial of a traditional Thai Herbal Remedy and Cannabis sativa oil. DOI: 10.1016/j.sleepx.2026.100173. PMCID: PMC12856596. PMID: 41623556. License: CC BY 4.0. https://pmc.ncbi.nlm.nih.gov/articles/PMC12856596/
- Schicktanz Nathalie (2025). Effects of a Valerian‐Hops Extract Combination (Ze 91019) on Sleep Duration and Daytime Cognitive and Psychological Parameters in Occasional Insomnia: A Randomized Controlled Feasibility Trial. DOI: 10.1002/brb3.70600. PMCID: PMC12134488. PMID: 40462685. License: CC BY 4.0. https://pmc.ncbi.nlm.nih.gov/articles/PMC12134488/

## Safety Note

Health information can change, and individual risk depends on medical history, medications, pregnancy status, age, and diagnosis. Talk with a qualified clinician before changing treatment, supplement, or medication routines.