# Calcium Supplementation: What the Evidence Says
Canonical: https://www.migaku.app/guides/calcium-supplementation-evidence-review
Category: evidence-review
Summary: Calcium Supplementation has 2 source documents in the current Migaku evidence database. The strongest available sources in this first pass are guideline, s
Last reviewed: 2026-05-01
Reviewed by: Migaku Evidence Review
# Calcium Supplementation: What the Evidence Says

## Quick Answer

Calcium Supplementation has 2 source documents in the current Migaku evidence database. The strongest available sources in this first pass are guideline, so conclusions should be framed as evidence-aware guidance rather than medical advice.

## Key Takeaways

- This page is generated only from sources stored in the Migaku evidence knowledge base.
- Current evidence mix: 1 guideline, 1 research article.
- Claims should be interpreted with the source type, study design, population, and publication date in mind.
- This article is educational and does not replace care from a qualified clinician.

## Evidence Map

| Source | Evidence type | Level | Date | Identifier |
| --- | --- | ---: | --- | --- |
| National Adoption of World Health Organization Recommendations on Calcium Supplementation During Pregnancy | guideline | 2 | 2025-11-03 | 10.1111/nyas.70120 |
| Does Calcium Supplementation Negate Erythropoiesis With Endurance Training? | research article | 4 | 2025-09-26 | 10.1111/apha.70108 |

## What The Sources Report

- HDP is associated with an increased risk of severe complications not only to the mother but also to the newborn. [Romero Iris B. (2025); evidence level 2]
- Women with a history of HDP have higher risk of developing cardiovascular disease later in life. [Romero Iris B. (2025); evidence level 2]
- We and others have observed that improved peak Oconsumption (VO) after ET is reverted to pre-training values following blood withdrawal to negate the ET-induced gain in Hb. [Guo Meihan (2025); evidence level 4]
- Circulating EPO was not increased with ET-Ca in men (20.1 ± 5.6 vs. [Guo Meihan (2025); evidence level 4]

## How To Read This Evidence

Evidence level 1 generally reflects systematic reviews or meta-analyses. Level 2 includes randomized trials, guidelines, or public-health guidance. Level 3 usually reflects observational or narrative-review evidence. Level 4 is weaker or early-stage evidence. The level is a sorting aid, not a final quality grade.

## Practical Interpretation

For calcium supplementation, the current source set is useful for orientation, but it is not yet broad enough for strong claims. Use cautious language and keep conclusions close to the cited sources.

## Limits Of This First Pass

This is a small-batch MVP article. It uses the first ingested sources for this topic and should be expanded with more targeted searches, license review, and human editorial checks before being treated as a definitive review.

## References

- Romero Iris B. (2025). National Adoption of World Health Organization Recommendations on Calcium Supplementation During Pregnancy. DOI: 10.1111/nyas.70120. PMCID: PMC12728327. PMID: 41183008. License: https://creativecommons.org/licenses/by-nc-nd/4.0/ http://creativecommons.org/licenses/by-nc-nd/4.0/ This is an open .... https://pmc.ncbi.nlm.nih.gov/articles/PMC12728327/
- Guo Meihan (2025). Does Calcium Supplementation Negate Erythropoiesis With Endurance Training?. DOI: 10.1111/apha.70108. PMCID: PMC12464794. PMID: 41000020. License: CC BY 4.0. https://pmc.ncbi.nlm.nih.gov/articles/PMC12464794/

## Safety Note

Health information can change, and individual risk depends on medical history, medications, pregnancy status, age, and diagnosis. Talk with a qualified clinician before changing treatment, supplement, or medication routines.