# Caffeine Performance Systematic Review: What the Evidence Says
Canonical: https://www.migaku.app/guides/caffeine-performance-systematic-review-evidence-review
Category: evidence-review
Summary: Caffeine Performance Systematic Review has 2 source documents in the current Migaku evidence database. The strongest available sources in this first pass are 
Last reviewed: 2026-07-30
Reviewed by: Migaku Evidence Review
# Caffeine Performance Systematic Review: What the Evidence Says

## Quick Answer

Caffeine Performance Systematic Review has 2 source documents in the current Migaku evidence database. The strongest available sources in this first pass are systematic review, so conclusions should be framed as evidence-aware guidance rather than medical advice.

## Key Takeaways

- This page is generated only from sources stored in the Migaku evidence knowledge base.
- Current evidence mix: 2 systematic review.
- Claims should be interpreted with the source type, study design, population, and publication date in mind.
- This article is educational and does not replace care from a qualified clinician.

## Evidence Map

| Source | Evidence type | Level | Date | Identifier |
| --- | --- | ---: | --- | --- |
| Caffeine and physical performance in female intermittent sport athletes: a systematic review and meta-analysis considering menstrual cycle phase | systematic review | 1 | 2026-05-22 | 10.3389/fnut.2026.1817134 |
| Effects of caffeine intake on exercise performance in basketball players: a systematic review and meta-analysis | systematic review | 1 | 2026-05-07 | 10.3389/fnut.2026.1837912 |

## What The Sources Report

- This is supported by evidence demonstrating caffeine's ergogenic effects on endurance exercise, short-term high intensity exercise, resistance exercise, team-sport performance, and ball sports. [Tan Zhi Sen (2026); evidence level 1]
- For example, increases in strength performance following caffeine has been associated with increased calcium ion (Ca) plasma concentrations as well as the alteration of carbohydrate and fat oxidation rate. [Tan Zhi Sen (2026); evidence level 1]
- A robust body of evidence supports its performance-enhancing effects across multiple exercise modalities, including endurance, anaerobic, resistance, and sprint-based activities. [Liu Jingxin (2026); evidence level 1]
- These ergogenic effects are attributed to a combination of central and peripheral mechanisms such as antagonism of adenosine receptors, increased neural drive, altered perception of effort, and enhanced muscle contractility. [Liu Jingxin (2026); evidence level 1]

## How To Read This Evidence

Evidence level 1 generally reflects systematic reviews or meta-analyses. Level 2 includes randomized trials, guidelines, or public-health guidance. Level 3 usually reflects observational or narrative-review evidence. Level 4 is weaker or early-stage evidence. The level is a sorting aid, not a final quality grade.

## Practical Interpretation

There is at least one systematic-review style source in the current set, so it deserves more weight than single-study evidence. For caffeine performance systematic review, the next editorial step is to add more targeted sources and separate strong findings from early or indirect evidence.

## Limits Of This First Pass

This is a small-batch MVP article. It uses the first ingested sources for this topic and should be expanded with more targeted searches, license review, and human editorial checks before being treated as a definitive review.

## References

- Tan Zhi Sen (2026). Caffeine and physical performance in female intermittent sport athletes: a systematic review and meta-analysis considering menstrual cycle phase. DOI: 10.3389/fnut.2026.1817134. PMCID: PMC13236873. PMID: 42253738. License: CC BY 4.0. https://pmc.ncbi.nlm.nih.gov/articles/PMC13236873/
- Liu Jingxin (2026). Effects of caffeine intake on exercise performance in basketball players: a systematic review and meta-analysis. DOI: 10.3389/fnut.2026.1837912. PMCID: PMC13191373. PMID: 42180581. License: CC BY 4.0. https://pmc.ncbi.nlm.nih.gov/articles/PMC13191373/

## Safety Note

Health information can change, and individual risk depends on medical history, medications, pregnancy status, age, and diagnosis. Talk with a qualified clinician before changing treatment, supplement, or medication routines.