# Caffeine Mental Performance Meta-analysis: What the Evidence Says
Canonical: https://www.migaku.app/guides/caffeine-mental-performance-meta-analysis-evidence-review
Category: evidence-review
Summary: Caffeine Mental Performance Meta-analysis has 2 source documents in the current Migaku evidence database. The strongest available sources in this first pass a
Last reviewed: 2026-06-24
Reviewed by: Migaku Evidence Review
# Caffeine Mental Performance Meta-analysis: What the Evidence Says

## Quick Answer

Caffeine Mental Performance Meta-analysis has 2 source documents in the current Migaku evidence database. The strongest available sources in this first pass are systematic review, so conclusions should be framed as evidence-aware guidance rather than medical advice.

## Key Takeaways

- This page is generated only from sources stored in the Migaku evidence knowledge base.
- Current evidence mix: 1 systematic review, 1 preclinical study.
- Claims should be interpreted with the source type, study design, population, and publication date in mind.
- This article is educational and does not replace care from a qualified clinician.

## Evidence Map

| Source | Evidence type | Level | Date | Identifier |
| --- | --- | ---: | --- | --- |
| Caffeine and physical performance in female intermittent sport athletes: a systematic review and meta-analysis considering menstrual cycle phase | systematic review | 1 | 2026-05-22 | 10.3389/fnut.2026.1817134 |
| Impact of Sleep Quality, Sleep Disturbances on Quality of Life Among Medical Students Worldwide: A Narrative Review | preclinical study | 4 | 2026-05-06 | 10.7759/cureus.108356 |

## What The Sources Report

- This is supported by evidence demonstrating caffeine's ergogenic effects on endurance exercise, short-term high intensity exercise, resistance exercise, team-sport performance, and ball sports. [Tan Zhi Sen (2026); evidence level 1]
- For example, increases in strength performance following caffeine has been associated with increased calcium ion (Ca) plasma concentrations as well as the alteration of carbohydrate and fat oxidation rate. [Tan Zhi Sen (2026); evidence level 1]
- Poor sleep quality among medical students has been increasingly associated with impaired well-being, psychological distress, and lower academic performance. [Muacevic Alexander (2026); evidence level 4]
- These patterns are particularly relevant in medical training, where academic demands, examinations, and clinical duties may contribute to reduced sleep duration and poorer sleep quality. [Muacevic Alexander (2026); evidence level 4]

## How To Read This Evidence

Evidence level 1 generally reflects systematic reviews or meta-analyses. Level 2 includes randomized trials, guidelines, or public-health guidance. Level 3 usually reflects observational or narrative-review evidence. Level 4 is weaker or early-stage evidence. The level is a sorting aid, not a final quality grade.

## Practical Interpretation

There is at least one systematic-review style source in the current set, so it deserves more weight than single-study evidence. For caffeine mental performance meta-analysis, the next editorial step is to add more targeted sources and separate strong findings from early or indirect evidence.

## Limits Of This First Pass

This is a small-batch MVP article. It uses the first ingested sources for this topic and should be expanded with more targeted searches, license review, and human editorial checks before being treated as a definitive review.

## References

- Tan Zhi Sen (2026). Caffeine and physical performance in female intermittent sport athletes: a systematic review and meta-analysis considering menstrual cycle phase. DOI: 10.3389/fnut.2026.1817134. PMCID: PMC13236873. PMID: 42253738. License: CC BY 4.0. https://pmc.ncbi.nlm.nih.gov/articles/PMC13236873/
- Muacevic Alexander (2026). Impact of Sleep Quality, Sleep Disturbances on Quality of Life Among Medical Students Worldwide: A Narrative Review. DOI: 10.7759/cureus.108356. PMCID: PMC13241278. PMID: 42255857. License: CC BY 4.0. https://pmc.ncbi.nlm.nih.gov/articles/PMC13241278/

## Safety Note

Health information can change, and individual risk depends on medical history, medications, pregnancy status, age, and diagnosis. Talk with a qualified clinician before changing treatment, supplement, or medication routines.