# Caffeine Cognitive Performance Randomized Trial: What the Evidence Says
Canonical: https://www.migaku.app/guides/caffeine-cognitive-performance-randomized-trial-evidence-review
Category: evidence-review
Summary: Caffeine Cognitive Performance Randomized Trial has 2 source documents in the current Migaku evidence database. The strongest available sources in this first 
Last reviewed: 2026-08-16
Reviewed by: Migaku Evidence Review
# Caffeine Cognitive Performance Randomized Trial: What the Evidence Says

## Quick Answer

Caffeine Cognitive Performance Randomized Trial has 2 source documents in the current Migaku evidence database. The strongest available sources in this first pass are randomized trial, so conclusions should be framed as evidence-aware guidance rather than medical advice.

## Key Takeaways

- This page is generated only from sources stored in the Migaku evidence knowledge base.
- Current evidence mix: 1 randomized trial, 1 research article.
- Claims should be interpreted with the source type, study design, population, and publication date in mind.
- This article is educational and does not replace care from a qualified clinician.

## Evidence Map

| Source | Evidence type | Level | Date | Identifier |
| --- | --- | ---: | --- | --- |
| Dose-Dependent Effects of Acute Caffeine Ingestion on Physical and Cognitive Performance in Trained Female Handball Players: A Randomized Crossover Study | randomized trial | 2 | 2026-06-05 | 10.3390/life16060954 |
| Effects of energy drinks on repeated sprint performance and cognitive function in athletes | research article | 4 | 2026-05-07 | 10.3389/fphys.2026.1796957 |

## What The Sources Report

- The studies in the literature show that increased physical and mental load disrupts attention resources, leading to decreased decision-making quality and increased technical errors. [Turgut Murat (2026); evidence level 2]
- This difference can likely be attributed to a speed-accuracy imbalance resulting from increased central nervous system stimulation. [Turgut Murat (2026); evidence level 2]
- Although there is a wide variety of supplements on the market, it is necessary to differentiate them according to scientific evidence supporting improved sports performance. [Liao Li An (2026); evidence level 4]
- Nonetheless, the temporary increase in exercise-induced cell damage associated with anserine, coupled with its improved antioxidant activity and hematological responses, indicates an enhanced adaptive response to exercise and better recovery. [Liao Li An (2026); evidence level 4]

## How To Read This Evidence

Evidence level 1 generally reflects systematic reviews or meta-analyses. Level 2 includes randomized trials, guidelines, or public-health guidance. Level 3 usually reflects observational or narrative-review evidence. Level 4 is weaker or early-stage evidence. The level is a sorting aid, not a final quality grade.

## Practical Interpretation

There is trial evidence in the current set, but population and intervention details still matter. For caffeine cognitive performance randomized trial, the next editorial step is to add more targeted sources and separate strong findings from early or indirect evidence.

## Limits Of This First Pass

This is a small-batch MVP article. It uses the first ingested sources for this topic and should be expanded with more targeted searches, license review, and human editorial checks before being treated as a definitive review.

## References

- Turgut Murat (2026). Dose-Dependent Effects of Acute Caffeine Ingestion on Physical and Cognitive Performance in Trained Female Handball Players: A Randomized Crossover Study. DOI: 10.3390/life16060954. PMCID: PMC13302302. PMID: 42355481. License: CC BY 4.0. https://pmc.ncbi.nlm.nih.gov/articles/PMC13302302/
- Liao Li An (2026). Effects of energy drinks on repeated sprint performance and cognitive function in athletes. DOI: 10.3389/fphys.2026.1796957. PMCID: PMC13189956. PMID: 42180830. License: CC BY 4.0. https://pmc.ncbi.nlm.nih.gov/articles/PMC13189956/

## Safety Note

Health information can change, and individual risk depends on medical history, medications, pregnancy status, age, and diagnosis. Talk with a qualified clinician before changing treatment, supplement, or medication routines.