# Ashwagandha and Stress: What the Evidence Says Canonical: https://www.migaku.app/guides/ashwagandha-stress-evidence-review Category: evidence-review Summary: Ashwagandha and Stress has 2 source documents in the current Migaku evidence database. The strongest available sources in this first pass are systematic revie Last reviewed: 2026-06-10 Reviewed by: Migaku Evidence Review # Ashwagandha and Stress: What the Evidence Says ## Quick Answer Ashwagandha and Stress has 2 source documents in the current Migaku evidence database. The strongest available sources in this first pass are systematic review, randomized trial, so conclusions should be framed as evidence-aware guidance rather than medical advice. ## Key Takeaways - This page is generated only from sources stored in the Migaku evidence knowledge base. - Current evidence mix: 1 systematic review, 1 randomized trial. - Claims should be interpreted with the source type, study design, population, and publication date in mind. - This article is educational and does not replace care from a qualified clinician. ## Evidence Map | Source | Evidence type | Level | Date | Identifier | | --- | --- | ---: | --- | --- | | Effects of Withania somnifera (L.) Dunal (Ashwagandha) on cognitive and physical function in adults: a systematic review and meta-analysis | systematic review | 1 | 2026-05-11 | 10.3389/fphar.2026.1799467 | | Efficacy and safety of Ashwagandha root extract sustained-release (AshwaSR) capsules in healthy adult, stressed subjects: A randomized, double-blind, placebo-controlled, parallel-group, 3-arm clinical trial | randomized trial | 2 | 2026-03-13 | 10.1097/MD.0000000000047990 | ## What The Sources Report - For example,evaluated nine randomized controlled trials by meta-analysis, and found that the scores of Perceived Stress Questionnaire (PSS), Anxiety Score (HAS) and serum cortisol levels were significantly reduced, indicating that it has a significant anti-pressure effect. [Zhu XiaoLing (2026); evidence level 1] - A study involving 80 healthy subjects aged 18-45 years showed that, compared with the placebo group, the Ashwagandha-supplemented group significantly improved bench press and leg lift strength, arm circumference and chest circumference, thigh circumference, and maximum oxygen uptake (VOmax) (p < 0.05). [Zhu XiaoLing (2026); evidence level 1] - There is a paucity of evidence assessing the efficacy and safety of low-dose formulations of Ashwagandha in stress management. [Thanawala Shefali (2026); evidence level 2] - We evaluated the efficacy and safety of AshwaSR capsules at doses of 150 and 300 mg in reducing stress and associated symptoms in healthy adults experiencing stress, over a period of 60 days of administration. [Thanawala Shefali (2026); evidence level 2] ## How To Read This Evidence Evidence level 1 generally reflects systematic reviews or meta-analyses. Level 2 includes randomized trials, guidelines, or public-health guidance. Level 3 usually reflects observational or narrative-review evidence. Level 4 is weaker or early-stage evidence. The level is a sorting aid, not a final quality grade. ## Practical Interpretation There is at least one systematic-review style source in the current set, so it deserves more weight than single-study evidence. There is trial evidence in the current set, but population and intervention details still matter. For ashwagandha stress randomized trial, the next editorial step is to add more targeted sources and separate strong findings from early or indirect evidence. ## Limits Of This First Pass This is a small-batch MVP article. It uses the first ingested sources for this topic and should be expanded with more targeted searches, license review, and human editorial checks before being treated as a definitive review. ## References - Zhu XiaoLing (2026). Effects of Withania somnifera (L.) Dunal (Ashwagandha) on cognitive and physical function in adults: a systematic review and meta-analysis. DOI: 10.3389/fphar.2026.1799467. PMCID: PMC13199302. PMID: 42199854. License: CC BY 4.0. https://pmc.ncbi.nlm.nih.gov/articles/PMC13199302/ - Thanawala Shefali (2026). Efficacy and safety of Ashwagandha root extract sustained-release (AshwaSR) capsules in healthy adult, stressed subjects: A randomized, double-blind, placebo-controlled, parallel-group, 3-arm clinical trial. DOI: 10.1097/MD.0000000000047990. PMCID: PMC12991725. PMID: 41824889. License: CC BY 4.0. https://pmc.ncbi.nlm.nih.gov/articles/PMC12991725/ ## Safety Note Health information can change, and individual risk depends on medical history, medications, pregnancy status, age, and diagnosis. Talk with a qualified clinician before changing treatment, supplement, or medication routines.